职称 副研究员

电话 13437159527

邮箱 gongyl@mail.hzau.edu.cn

政治面貌：中共党员

研究方向 水产动物代谢调控&新饲料蛋白源开发

教育经历

2015年9月至2021年1月在中国科学院水生生物研究所学习，获博士学位；

2019年10月至2020年10月在美国范德堡大学医学院联合培养博士；

2011年9月至2015年6月在华中农业大学51菠菜网学习，获学士学位。

主要职历

2023年12月-至今，51菠菜网，副研究员；

2023年5月-2023年11月，复旦大学生物医学研究院，博士后；

2021年2月-2023年4月，中国科学院水生生物研究所，博士后；

科研成果

主持和参与的科研项目：

1.中国博士后科学基金面上资助（2022M713324），执行期间：2022.06-2024.06，主持

2.湖北省博士后创新研究岗位，执行期间：2021.09-2023.09，主持

3.国家自然科学基金面上项目（31972771），执行期间：2020.01-2023.12，参与

4.国家特色淡水鱼产业技术体系岗位科学家（CARS-46），执行期间：2021-2025，参与

发表的科研论文：

1.Yulong Gong#, Bingyuan Yang#, Dingdong Zhang, Yue Zhang, Zihan Tang, Liu Yang, Katie C Coates, Linlin Yin, Brittney A Covington, Ravi S Patel, Walter A Siv, Katelyn Sellick, Matthew Shou, Wenhan Chang, E Danielle Dean, Alvin C Powers, Wenbiao Chen. Hyperaminoacidemia induces pancreatic α cell proliferation via synergism between mTORC1 and CaSR-Gq signaling pathways. Nature Communications 2023, 14: 235.

2.Yulong Gong, Bingyuan Yang, Wenbiao Chen. Systematic genome editing of the genes spanning an entire chromosome by CRISPR/Cas9 in a vertebrate—zebrafish (Danio rerio). Science China life sciences 2020, s11427-020-1639-4.

3.Yulong Gong#, Qisheng Lu#, Longwei Xi, Yulong Liu, Bingyuan Yang, Jingzhi Su, Haokun Liu, Junyan Jin, Zhimin Zhang, Yunxia Yang, Xiaoming Zhu, Shouqi Xie, and Dong Han*. F6P/G6P-mediated ChREBP activation promotes the insulin resistance-driven hepatic lipid deposition in zebrafish. Journal of Nutritional Biochemistry 2023, 122: 109452.

4.Yulong Gong, Weijun Chen, Dong Han*, Xiaoming Zhu, Yunxia Yang, Junyan Jin, Haokun Liu, Shouqi Xie. Effects of food restriction on growth, body composition and gene expression related in regulation of lipid metabolism and food intake in grass carp. Aquaculture 2017, 469: 28-35.

5.Yulong Gong, Longwei Xi, Yulong Liu, Qisheng Lu, Zhimin Zhang, Haokun Liu, Junyan Jin, Yunxia Yang, Xiaoming Zhu, Shouqi Xie*, Dong Han*. Sequential activations of ChREBP and SREBP1 signals regulate the high carbohydrate diet-induced hepatic lipid deposition in gibel carp (Carassius gibelio). Aquaculture Nutrition 2023, 6672985.

6.Bingyuan Yang#, Gang Zhai#, Yulong Gong#, Jingzhi Su, Xuyan Peng, Guohui Shang, Dong Han*, Junyan Jin, Haokun Liu, Zhenyu Du, Zhan Yin, and Shouqi Xie. Different physiological roles of insulin receptors in mediating nutrient metabolism in zebrafish. American Journal of Physiology-Endocrinology and Metabolism 2018, 315: E38-E51.

7.Yulong Gong#, Gang Zhai#, Jingzhi Su, Bingyuan Yang, Junyan Jin, Haokun Liu, Zhan Yin*, Shouqi Xie, Dong Han*. Different roles of insulin receptor a and b in maintaining blood glucose homeostasis in zebrafish. General and Comparative Endocrinology 2018, 269:33-45.

8.Yulong Gong, Fan Yang, Junpeng Hu, Cui Liu, Haokun Liu*, Dong Han, Junyan Jin, Yunxia Yang, Xiaoming Zhu, Jianhua Yi, Shouqi Xie. Effects of dietary yeast hydrolysate on the growth, antioxidant response, immune response and disease resistance of largemouth bass (Micropterus salmoides). Fish & Shellfish Immunology 2019, 94:548-557.

9.Yulong Gong, Qisheng Lu, Yulong Liu, Longwei Xi, Zhimin Zhang, Haokun Liu, Junyan Jin, Yunxia Yang, Xiaoming Zhu, Shouqi Xie, Dong Han. Dietary berberine alleviates high carbohydrate diet-induced intestinal damages and improves lipid metabolism in largemouth bass (Micropterus salmoides). Frontiers in Nutrition 2022, 23:1010859.

10.Qisheng Lu#, Yulong Gong#, Longwei Xi, Yulong Liu, Wenjie Xu, Haokun Liu, Junyan Jin, Zhimin Zhang, Yunxia Yang, Xiaoming Zhu, Shouqi Xie, Dong Han. Feed restriction alleviates chronic thermal stress-induced liver oxidation and damages via reducing lipid accumulation in channel catfish (Ictalurus punctatus). Antioxidants 2022,11:980.

11.Bingyuan Yang#, Gang Zhai#, Yulong Gong, Jingzhi Su, Dong Han*, Zhan Yin, Shouqi Xie. Depletion of insulin receptors leads to β-cell hyperplasia in zebrafish. Science Bulletin 2017, 62: 486-492.

12.Bingyuan Yang, Liu Yang, Yueyang Wang, Lisette A. Maddison, Zihan Tang, Sander Haigh, Yulong Gong, Yue Zhang, Brittney A. Covington, Karin J. Bosma, Xin Tong, Patrick Page-McCaw, Maureen Gannon, Qing Deng, Wenbiao Chen. Macrophages and neutrophils are necessary for ER stress-induced β cell loss. Cell Reports 2022, 40, 111255.

授权和申请专利：

1. 刘翠; 刘昊昆; 朱晓鸣; 解绶启; 韩冬; 巩玉龙; 金俊琰; 张志敏 ; 一种提高氮磷利用率、降低氮磷排放的水产养殖装置, 2023-1-03, 中国, ZL202221862659.4

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